Structure of PDB 6y32 Chain D

Receptor sequence
>6y32D (length=305) Species: 9606 (Homo sapiens) [Search protein sequence]
MGSLSREDMESVLDKMRDHLIAKNVAADIAVQLCESVANKLEGTFSTVTS
TVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYVVTFCGVNGVGKST
NLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEKHGG
RTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMT
ALAKLITVNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLID
GIVLTKFDTIDDKVGAAISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVA
ALMKA
3D structure
PDB6y32 Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia.
ChainD
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP D N427 R458 N94 R125
BS02 GNP D N427 G428 G430 K431 S432 T433 N434 R458 K589 D591 G615 G617 Q618 N94 G95 G97 K98 S99 T100 N101 R125 K256 D258 G282 G284 Q285
Gene Ontology
Molecular Function
GO:0005525 GTP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6y32, PDBe:6y32, PDBj:6y32
PDBsum6y32
PubMed33053321
UniProtP08240|SRPRA_HUMAN Signal recognition particle receptor subunit alpha (Gene Name=SRPRA)

[Back to BioLiP]