Structure of PDB 6xr5 Chain D

Receptor sequence
>6xr5D (length=393) Species: 235443 (Cryptococcus neoformans var. grubii H99) [Search protein sequence]
HMVHEATASAPVNIACIKYWGKRDTRLILPTNSSLSVTLDQDHLRSTTTS
RADASFEAGDRLWLNGREEAIKEGGRLAVCIKELRAWRKEMETKDKNLPK
LSEWPLRIASYNNFPTAAGLASSASGLAALVASLASLYSLPQSPSQLSLV
ARQGSGSACRSLFGGFVAWREGTDPAGSDSLAEEVAPREHWPEMHALICV
VSDAKSSTSGMQKTVETSTLLQERLRVVPKRMDAISQAIKARDFAEFAKL
TMADSNSFHAVCLDTAPPIFYLNDVSRAIIAVVEELNRAAGEIIAAYTFD
AGPNAVIYTLEKNMPFVLGAIKRFFPTSEEFESPFQTGVRDLPEGFNTGV
VREGGWEKGAVKGLIHTRVGDGPRVLEKEDSLLGENGVPKVLA
3D structure
PDB6xr5 Crystal Structure of Diphosphomevalonate decarboxylase (MVD1) from Cryptococcus neoformans var. grubii serotype A
ChainD
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.1.33: diphosphomevalonate decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADE D L63 S109 S121 G125 L64 S110 S122 G126
Gene Ontology
Molecular Function
GO:0004163 diphosphomevalonate decarboxylase activity
GO:0005524 ATP binding
GO:0016829 lyase activity
GO:0016831 carboxy-lyase activity
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0016126 sterol biosynthetic process
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6xr5, PDBe:6xr5, PDBj:6xr5
PDBsum6xr5
PubMed
UniProtJ9VRT5

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