Structure of PDB 6x8k Chain D

Receptor sequence
>6x8kD (length=92) Species: 9606 (Homo sapiens) [Search protein sequence]
HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMH
ILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY
3D structure
PDB6x8k Caspase-3 in complex with elongated ketomethylene inhibitor
ChainD
Resolution2.17 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D Y204 S205 W206 R207 N208 S209 S249 Y20 S21 W22 R23 N24 S25 S65
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6x8k, PDBe:6x8k, PDBj:6x8k
PDBsum6x8k
PubMed
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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