Structure of PDB 6whv Chain D

Receptor sequence
>6whvD (length=784) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SIGIAVILVGTSDEVAIKDAHEKDDFHHLSVVPRVELVAMNETDPKSIIT
RICDLMSDRKIQGVVFADDTDQEAIAQILDFISAQTLTPILGIHGGSSMI
MADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFV
NKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQNQLKKLQSPIILLYCT
KEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDTVPSEFPTGLISVSYD
EWDYGLPARVRDGIAIITTAASDMLSEHSFIPEPKSSCYNTHEKRIYQSN
MLNRYLINVTFEGRDLSFSEDGYQMHPKLVIILLNKERKWERVGKWKDKS
LQMKYYVWPRMDDHLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRII
SENDEEPGYIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKKINGT
WNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNG
TVSPSAFLEPFSACVWVMMFVMLLIVSAVAVFVFEYPSFTIGKAIWLLWG
LVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVD
QVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNNYAEMHAYMGKFNQ
RGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTG
YGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHNEKNEVMSS
QLDIDNMAGVFYMLGAAMALSLITFISEHLFYWQ
3D structure
PDB6whv Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
ChainD
Resolution4.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QGP D E413 A414 H486 T514 R519 G689 S690 T691 Y762 E372 A373 H443 T471 R476 G628 S629 T630 Y701
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0038023 signaling receptor activity
Biological Process
GO:0006811 monoatomic ion transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6whv, PDBe:6whv, PDBj:6whv
PDBsum6whv
PubMed32610085
UniProtQ00960|NMDE2_RAT Glutamate receptor ionotropic, NMDA 2B (Gene Name=Grin2b)

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