Structure of PDB 6whg Chain D

Receptor sequence
>6whgD (length=523) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
GFEAPTPRQILRVTLNLKYLIDKVVPIVYILSPKVVKLAYEACGGNPKDK
ANKRKYQSVIIFSLLKVCEWYSILATMEVHNAKLYETRNLASQQLCKLLI
EREETRDLQFLFMQLLLRRYVINENDEDQEPLNALELATDMHCTTVIGSS
GFQRCLKWIWRGWIVQNGLDPTTFIKDDSLAFNPVRLKAPVYQNYLQMIF
SFLFLGLYTLVVNGKDSERVQSFDLLESIFYVFNTGFILDELTKLYYIGY
AHLSFWNLFNDTTYLIITFAMGFRAMSVTPYSSEDWDKISYRVLSCAAPF
VWSRLLLYLESQRFIGIMLVILKHMMKESIVFFFLLFLIMIGFTQGFLGL
DSADGKRDITGPILGNLTITVLGLGSFDVFEEFAPPYAAILYYGYYFIVS
VILLNILIALYSTAYQKVIDNADDEYMALMSQKTLRYIRKDLSYTVMTIV
YSPFLLLISVKETREARRIKYNRMKRLNDDANEYDTPWDLTDGYLDDNRN
SGMRATQLKNSRSLKLQRTAEQE
3D structure
PDB6whg Structure of the ancient TRPY1 channel from Saccharomyces cerevisiae reveals mechanisms of modulation by lipids and calcium.
ChainD
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA D D398 D401 K403 D405 D351 D354 K356 D358
BS02 CA D T563 D566 D569 Q591 T486 D489 D492 Q507
BS03 PWE D S297 F298 W299 F302 P346 F347 S350 L354 E357 L366 K370 L476 Q479 R483 S254 F255 W256 F259 P299 F300 S303 L307 E310 L319 K323 L429 Q432 R436
Gene Ontology
Molecular Function
GO:0005227 calcium-activated cation channel activity
GO:0005244 voltage-gated monoatomic ion channel activity
GO:0005262 calcium channel activity
GO:0005267 potassium channel activity
GO:0005272 sodium channel activity
Biological Process
GO:0030003 intracellular monoatomic cation homeostasis
GO:0035725 sodium ion transmembrane transport
GO:0070588 calcium ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
GO:0097553 calcium ion transmembrane import into cytosol
Cellular Component
GO:0000324 fungal-type vacuole
GO:0000329 fungal-type vacuole membrane
GO:0005773 vacuole
GO:0005774 vacuolar membrane
GO:0016020 membrane
GO:1990816 vacuole-mitochondrion membrane contact site

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Molecular Function
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Cellular Component
External links
PDB RCSB:6whg, PDBe:6whg, PDBj:6whg
PDBsum6whg
PubMed34453887
UniProtQ12324|YVC1_YEAST Calcium channel YVC1 (Gene Name=YVC1)

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