Structure of PDB 6wcx Chain D

Receptor sequence
>6wcxD (length=255) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
GPGAYISLNYHSPTIGMHQNLTVILPEDQSFFNSDTTVKPLKTLMLLHGL
SSDETTYMRYTSIERYANEHKLAVIMPNVDHSAYANMAYGHSYYDYILEV
YDYVHQIFPLSKKRDDNFIAGHSMGGYGTIKFALTQGDKFAKAVPLSAVF
EAQNLMDLEWNDFSKEAIIGNLSSVKGTEHDPYYLLDKAVAEDKQIPKLL
IMCGKQDFLYQDNLDFIDYLSRINVPYQFEDGPGDHDYAYWDQAIKRAIT
WMVND
3D structure
PDB6wcx Structural Basis for the Inhibitor and Substrate Specificity of the Unique Fph Serine Hydrolases of Staphylococcus aureus .
ChainD
Resolution2.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.2.12: S-formylglutathione hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HE4 D G47 L48 S121 M122 N152 G49 L50 S123 M124 N154
Gene Ontology
Molecular Function
GO:0016788 hydrolase activity, acting on ester bonds
GO:0018738 S-formylglutathione hydrolase activity
Biological Process
GO:0046294 formaldehyde catabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6wcx, PDBe:6wcx, PDBj:6wcx
PDBsum6wcx
PubMed32865965
UniProtQ2FUY3

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