Structure of PDB 6w6j Chain D

Receptor sequence
>6w6jD (length=707) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
FNPTTKTQAALTAALQAASTAGNPEIRPAHLLMALLTQNDGIAAPLLEAV
GVEPATVRAETQRLLDRLPQQPQLSRESLAAITTAQQLATELDDEYVSTE
HVMVGLATGDSDVAKLLTGHGASPQALREAFVKVRGTSPEPEATYQALQK
YSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEPGVGKT
AIVEGLAQRIVAGDVPESLRDKTIVALDLGSMVAGSKYRGEFEERLKAVL
DDIKNSAGQIITFIDELHTIVGAGADAGNMIKPMLARGELRLVGATTLDE
YRKHIEKDAALERRFQQVYVGEPSVEDTIGILRGLKDRYEVHHGVRITDS
ALVAAATLSDRYITARFLPDKAIDLVDEAASRLRMEIDSRPKEEVGPDDI
ADVVSAWTGIPAGRLLEGETAKLLRMEDELGKRVIGQKAAVTAVSDAVRR
SRAGVSDPNRPTGAFMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSE
YGEKHTVARLIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDV
FDVLLQVLDEGRLTDGHGRTVDFRNTILILTSNLGSGGSAEQVLAAVRAT
FKPEFINRLDDVLIFEGLNPEELVRIVDIQLAQLGKRLAQRRLQLQVSLP
AKRWLAQRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNV
SPDADSL
3D structure
PDB6w6j Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
ChainD
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D Y251 Y655 V656 Y238 Y517 V518
BS02 AGS D R332 R333 R313 R314
BS03 AGS D V180 I181 G211 K212 L354 V167 I168 G198 K199 L335
BS04 AGS D R571 I573 G610 V611 G612 K613 T614 E615 Q768 R433 I435 G472 V473 G474 K475 T476 E477 Q630
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0009408 response to heat
GO:0034605 cellular response to heat
GO:0042026 protein refolding
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w6j, PDBe:6w6j, PDBj:6w6j
PDBsum6w6j
PubMed34038719
UniProtP9WPD1|CLPB_MYCTU Chaperone protein ClpB (Gene Name=clpB)

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