Structure of PDB 6vgd Chain D

Receptor sequence
>6vgdD (length=117) Species: 9606 (Homo sapiens) [Search protein sequence]
AELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGN
DENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQV
ATYHRAIKVTVDGPREP
3D structure
PDB6vgd Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins.
ChainD
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D R131 K134 T135 R186 R193 R225 R21 K24 T25 R76 R83 R115
BS02 dna D R190 R193 G194 K218 T220 V221 D222 R80 R83 G84 K108 T110 V111 D112
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005524 ATP binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6vgd, PDBe:6vgd, PDBj:6vgd
PDBsum6vgd
PubMed33275876
UniProtQ13950|RUNX2_HUMAN Runt-related transcription factor 2 (Gene Name=RUNX2)

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