Structure of PDB 6uj8 Chain D

Receptor sequence
>6uj8D (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
SHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPW
IEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGC
DVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAR
EAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPS
GEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB6uj8 Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens.
ChainD
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D Y7 N63 Y67 Q70 E76 S77 N80 Y84 Y99 D114 Y116 Y123 T143 W147 E152 R156 Y159 W167 Y171 Y6 N62 Y66 Q69 E75 S76 N79 Y83 Y98 D113 Y115 Y122 T142 W146 E151 R155 Y158 W166 Y170
External links
PDB RCSB:6uj8, PDBe:6uj8, PDBj:6uj8
PDBsum6uj8
PubMed34489470
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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