Structure of PDB 6u82 Chain D

Receptor sequence
>6u82D (length=134) Species: 9606 (Homo sapiens) [Search protein sequence]
GRGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIW
FQNERSRQLRQHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKD
RFPGIAAREELARETGLPESRIQIWFQNRRARHP
3D structure
PDB6u82 DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD.
ChainD
Resolution3.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D R20 R21 R23 L24 W26 Y43 R49 R62 Q64 W66 R71 R76 R79 R80 R95 R96 R98 T99 R124 R137 W141 Q143 R146 R4 R5 R7 L8 W10 Y27 R33 R46 Q48 W50 R55 R60 R63 R64 R79 R80 R82 T83 R108 R121 W125 Q127 R130
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6u82, PDBe:6u82, PDBj:6u82
PDBsum6u82
PubMed32020675
UniProtQ9UBX2|DUX4_HUMAN Double homeobox protein 4 (Gene Name=DUX4)

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