Structure of PDB 6u78 Chain D

Receptor sequence
>6u78D (length=419) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
PQELAALHARHQQDYAALQGMKLALDLTRGKPSAEQLDLSNQLLSLPGDD
YRDPEGTDTRNYGGQHGLPGLRAIFAELLGIAVPNLIAGNNSSLELMHDI
VAFSMLYGGVDSPRPWIQEQDGIKFLCPVPGYDRHFAITETMGIEMIPIP
MLQDGPDVDLIEELVAVDPAIKGMWTVPVFGNPSGVTYSWETVRRLVQMR
TAAPDFRLFWDNAYAVHTLTLDFPRQVDVLGLAAKAGNPNRPYVFASTSK
ITFAGGGVSFFGGSLGNIAWYLQYAGKKSIGPDKVNQLRHLRFFGDADGV
RLHMLRHQQILAPKFALVAEVLDQRLSESKIASWTEPKGGYFISLDVLPG
TARRTVALAKDVGIAVTEAGASFPYRKDPDDKNIRIAPSFPSVPDLRNAV
DGLATCALLAATETLLNQG
3D structure
PDB6u78 Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis.
ChainD
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.1: aspartate transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP D S99 S100 L101 Y139 D218 A220 Y221 S254 S256 K257 S92 S93 L94 Y132 D211 A213 Y214 S247 S249 K250
Gene Ontology
Molecular Function
GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity
GO:0008483 transaminase activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:6u78, PDBe:6u78, PDBj:6u78
PDBsum6u78
PubMed32327655
UniProtO69689|ASPAT_MYCTU Aspartate aminotransferase (Gene Name=Rv3722c)

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