Structure of PDB 6tug Chain D

Receptor sequence
>6tugD (length=406) Species: 888064 (Enterococcus italicus DSM 15952) [Search protein sequence]
AMKILFSPIGNTDPWRNDRDGAMLHIVRHYQPDRVVLFFTESIWQGNQGQ
QAFDWVKIIQSINENCQIEIKCDTIEVENDFDAYKDLFHQYLVEEKRKYP
NAEIFLNVTSGTPQMETTLCLEYVTYPDKMRCIQVSTPLYAQADCQEVDL
EIVNEEESQQPSRCHKIAILSFREAIVRNQIKSLLDNYDYEAALQLVASQ
KSFRNGKEIRKKLKELIDDIKMHRVFSYLIKQYPRNEKLQKALLHTILLE
MRHQRGDIAETLIRVKSIAEYIVEQYIQKNYPYLIIYKEDKPYFNVSYSQ
ELTESYLALMDLDRILGFPAYRDFLQLLEASNEMTNEMNKVNEINNLRNK
VAHNLDSLNLDRDKNGRKITNAVTAVRTMLLAVFPEVQENDFHYLKQFNQ
SIKELL
3D structure
PDB6tug Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6.
ChainD
Resolution2.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AF2 D E80 N81 P115 E78 N79 P113
BS02 AF2 D N10 T39 I42 G113 T114 N11 T40 I43 G111 T112
BS03 AF2 D T11 T111 P140 T12 T109 P138
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6tug, PDBe:6tug, PDBj:6tug
PDBsum6tug
PubMed32221291
UniProtE6LHV2|CSM6_ENTI1 CRISPR system endoribonuclease Csm6 (Gene Name=csm6)

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