Structure of PDB 6t7j Chain D

Receptor sequence
>6t7jD (length=629) Species: 246969 (Thermococcus sp. AM4) [Search protein sequence]
YIKYRVPAKGVSATKGVAELIEKAEEEGIKTAWHRLLEQQPQCAFGQLGV
CCRNCAMGPCRIDPFGSGPTKGVCGAGADTIVARNLLRMIAAGAAAHSDH
ARDVVEVFKGVAEGRFQYYKLTDVEKLKSLAETLGISTEGKDEHEIAREL
AEVLEWEFGKPGDEPLRMLALAPKKRIKVWEKAGVLPRAIDREVCECMHR
THIGVDADPVSLLLHGIRTSLADGWSGSMMATYLSDILFGTPKPLKAEAN
LGVLKEDYVNIVVHGHNPILSTKIAEIAMSEEMQKFAKKYGAKGVNVVGM
CCTGNEVLMRLGVPIAGSFLMQELAIITGAVEAIIVDYQCIMPAIVDVAQ
CYHTKVITTEPKGHIPGAVHIEFNAEKADEIAKEIVRIAIENYPNRPRDR
VHIPKHKMEAIAGFSVEAIVEALGGTLEPLINALRDGTIKGIVGIVGCNN
PKVKHNYSHVTLAKELIKRDVLVVGTGCWSIAAAMEGLMSPKAVDLAGPG
LKKICEALNIPPCLHMGSCVDCSRILIALGALADALGVDISDLPAAGSAP
EWMSEKAVSIGTYFVASGVFTHLGVVPPVMGSQKVAKILTEDVEDIIGGK
FYVEPDPVKAAETIYNVILEKRKKLGWPL
3D structure
PDB6t7j The two CO-dehydrogenases of Thermococcus sp. AM4.
ChainD
Resolution2.43 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.2.7.4: anaerobic carbon-monoxide dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 D C55 C58 M60 G61 C63 V76 C77 R87 I206 C52 C55 M57 G58 C60 V73 C74 R84 I203
BS02 FES D C46 C54 R56 C43 C51 R53
BS03 MSK D H269 C305 F322 C343 G450 C451 C481 C522 K559 H266 C302 F319 C340 G447 C448 C478 C519 K556
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004601 peroxidase activity
GO:0016151 nickel cation binding
GO:0016491 oxidoreductase activity
GO:0043885 anaerobic carbon-monoxide dehydrogenase activity
GO:0046872 metal ion binding
GO:0050418 hydroxylamine reductase activity
GO:0051537 2 iron, 2 sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0042542 response to hydrogen peroxide
GO:0098869 cellular oxidant detoxification

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Molecular Function
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Biological Process
External links
PDB RCSB:6t7j, PDBe:6t7j, PDBj:6t7j
PDBsum6t7j
PubMed32209322
UniProtB7R5K0

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