Structure of PDB 6s05 Chain D

Receptor sequence

>6s05D (length=361) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

SRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYA
VSEKAGHQTSAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFA
PTKTWRKWNVKVNHNEKRYATASAIAATAVASLVLARGHRVEKIPEIPLV
VSTDLESIQKTKEAVAALKAVGAHSDLLKVLKSKKLRAGKGKYRNRRWTQ
RRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAPGAHLGRFVIWT
EAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIRP
AGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKAEKTGTKP
AAVFTETLKHD

3D structure

PDB

6s05 Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.

Chain

Resolution

3.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	D	R31 H36 T40 N45 K46 Q48 Y50 V52 S53 E54 A56 G57 H58 Q59 T60 S61 T67 G68 V71 A72 R73 I74 P75 G81 T82 R84 Q87 N92 M93 R95 R98 M99 F100 A101 K104 W106 R107 K108 K112 N114 H115 E117 K118 R119 Y120 R138 R141 K161 T162 K183 K186 L187 R188 A189 G190 K191 K193 Y194 R195 N196 R197 W199 R202 R203 Y209 V216 K217 N221 P223 T227 A228 S232 N234 P240 G241 H243 K271 V272 I290 N291 R300 T306 Q307 K308 R309 V312 K315 N320 Q322 L324 R326 A331 F334 A335 S341 K342 K343 A344 T347 T349 L359	R30 H35 T39 N44 K45 Q47 Y49 V51 S52 E53 A55 G56 H57 Q58 T59 S60 T66 G67 V70 A71 R72 I73 P74 G80 T81 R83 Q86 N91 M92 R94 R97 M98 F99 A100 K103 W105 R106 K107 K111 N113 H114 E116 K117 R118 Y119 R137 R140 K160 T161 K182 K185 L186 R187 A188 G189 K190 K192 Y193 R194 N195 R196 W198 R201 R202 Y208 V215 K216 N220 P222 T226 A227 S231 N233 P239 G240 H242 K270 V271 I289 N290 R299 T305 Q306 K307 R308 V311 K314 N319 Q321 L323 R325 A330 F333 A334 S340 K341 K342 A343 T346 T348 L358
BS02	rna	D	A51 K193 Y194	A50 K192 Y193

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6s05, PDBe:6s05, PDBj:6s05
PDBsum	6s05
PubMed	31115337
UniProt	P10664\|RL4A_YEAST Large ribosomal subunit protein uL4A (Gene Name=RPL4A)

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