Structure of PDB 6rxm Chain D

Receptor sequence
>6rxmD (length=227) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
KPRVLVLTGAGISAESGIGLWEEHRVEDVGTPEGFDRDPELVQAFYNARR
RQLQQPEIQPNAAHLALAKLQDALGDRFLLVTQNCDNLHERAGNTNVIHM
HGELLKVRCSQSGQALDWTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLG
MDEIYMALSMADIFIAIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQV
GNEFAEKYYGPASQVVPEFVEKLLKGL
3D structure
PDB6rxm Evolved, Selective Erasers of Distinct Lysine Acylations.
ChainD
Resolution1.92 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.286: protein acetyllysine N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D E79 G191 E33 G145
BS02 peptide D H147 V188 W189 F190 G191 E192 M193 Y201 G217 H218 V219 Y220 P221 Q245 H101 V142 W143 F144 G145 E146 M147 Y155 G171 H172 V173 Y174 P175 Q199
BS03 ZN D C155 C174 C177 C109 C128 C131
Gene Ontology
Molecular Function
GO:0036054 protein-malonyllysine demalonylase activity
GO:0036055 protein-succinyllysine desuccinylase activity
GO:0070403 NAD+ binding

View graph for
Molecular Function
External links
PDB RCSB:6rxm, PDBe:6rxm, PDBj:6rxm
PDBsum6rxm
PubMed32187803
UniProtP75960|NPD_ECOLI NAD-dependent protein deacylase (Gene Name=cobB)

[Back to BioLiP]