Structure of PDB 6rwo Chain D

Receptor sequence
>6rwoD (length=207) Species: 11723 (Simian immunodeficiency virus) [Search protein sequence]
SPKTWQMDCTHLEGKVIIVAVHVASGYIEAEVLPAETGKETAHFLLKLAA
RWPVKHLHTDNGDNFTSSAVQAVCWWAQIEHTFSVVESMNHQLKTIITQI
RDQAEKIETAVQMAVLIHNFKRKGGIGGYSAGERIIDIIASDLQTTKLQN
QISKIQNFRVYFREGRDQQWKGPATLIWKGEGAVVIQDGQDLKVVPRRKC
KIIKDYG
3D structure
PDB6rwo Structural basis of second-generation HIV integrase inhibitor action and viral resistance.
ChainD
Resolution3.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D R228 R263 R163 R198
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:6rwo, PDBe:6rwo, PDBj:6rwo
PDBsum6rwo
PubMed32001525
UniProtE1ANT8

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