Structure of PDB 6rft Chain D

Receptor sequence
>6rftD (length=403) Species: 36809 (Mycobacteroides abscessus) [Search protein sequence]
ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHD
GKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQ
LADIRSRGESLAMLFASEALIYGRFGYGVATESAELSGQVRELAFRPTVD
LGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEEL
QKESGKVRFVLHYESDGTASGFAIYRPKPGNAELHVQEVLGTNPRSYART
WRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIP
RALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADI
ALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAP
DDF
3D structure
PDB6rft Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacterium abscessus.
ChainD
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACO D V85 R90 R91 G93 L95 T96 E120 L122 I123 R126 V83 R88 R89 G91 L93 T94 E118 L120 I121 R124
Gene Ontology
Molecular Function
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0034069 aminoglycoside N-acetyltransferase activity
Biological Process
GO:0030649 aminoglycoside antibiotic catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6rft, PDBe:6rft, PDBj:6rft
PDBsum6rft
PubMed31254444
UniProtA0A1M9A4M7

[Back to BioLiP]