Structure of PDB 6r72 Chain D

Receptor sequence
>6r72D (length=572) Species: 1423 (Bacillus subtilis) [Search protein sequence]
SKLKPFFALVRRTNPSYGKLAFALALSVVTTLVSLLIPLLTKQLVDGFSM
SNLSGTQIGLIALVFFVQAGLSAYATYALNYNGQKIISGLRELLWKKLIK
LPVSYFDTNASGETVSRVTNDTMVVKELITTHISGFITGIISVIGSLTIL
FIMNWKLTLLVLVVVPLAALILVPIGRKMFSISRETQDETARFTGLLNQI
LPEIRLVKASNAEDVEYGRGKMGISSLFKLGVREAKVQSLVGPLISLVLM
AALVAVIGYGGTAGALVAFILYLFQIIMPMGQITTFFTQLQKSIGATERM
IEILAEEEEDTVTGKQIENAHLPIQLDRVSFGYKPDQLILKEVSAVIEAG
KVTAIVGPSGGGKTTLFKLLERFYSPTAGTIRLGDEPVDTYSLESWREHI
GYVSQESPLMSGTIRENICYGLERDVTDAEIEKAAEMAYALNFIKELPNQ
FDTEVGERGIMLSGGQRQRIAIARALLRNPSILMLDAATSSLDSQSEKSV
QQALEVLMEGRTTIVIAHRLSTVVDADQLLFVEKGEITGRGTHHELMASH
GLYRDFAEQQLKMNADLENKAG
3D structure
PDB6r72 Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter.
ChainD
Resolution3.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.6.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP D L464 I477 M478 S480 G481 G482 L447 I460 M461 S463 G464 G465
BS02 ATP D D116 Y350 S376 G377 G378 G379 K380 T381 T382 K385 Q422 D107 Y333 S359 G360 G361 G362 K363 T364 T365 K368 Q405
BS03 MG D T381 Q422 T364 Q405
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0034040 ATPase-coupled lipid transmembrane transporter activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0006869 lipid transport
GO:0046677 response to antibiotic
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:6r72, PDBe:6r72, PDBj:6r72
PDBsum6r72
PubMed35080979
UniProtO06967|BMRA_BACSU Multidrug resistance ABC transporter ATP-binding/permease protein BmrA (Gene Name=bmrA)

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