Structure of PDB 6qtz Chain D

Receptor sequence

>6qtzD (length=361) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

SRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYA
VSEKAGHQTSAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFA
PTKTWRKWNVKVNHNEKRYATASAIAATAVASLVLARGHRVEKIPEIPLV
VSTDLESIQKTKEAVAALKAVGAHSDLLKVLKSKKLRAGKGKYRNRRWTQ
RRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAPGAHLGRFVIWT
EAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIRP
AGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKAEKTGTKP
AAVFTETLKHD

3D structure

PDB

6qtz Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.

Chain

Resolution

3.5 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	D	R31 H36 N43 K44 N45 K46 R47 Q48 Y50 V52 S53 A56 H58 Q59 T60 S61 T67 G68 R69 V71 R73 I74 P75 R76 G80 G81 T82 R84 Q87 N92 M93 R95 G96 R98 M99 F100 A101 P102 K104 R107 K108 V111 N114 H115 N116 E117 K118 R119 R138 G139 R141 K161 T162 S176 L179 K180 K186 L187 R188 A189 G190 K191 K193 Y194 R195 N196 R197 W199 R202 R203 Y209 K217 N221 T227 S232 N234 G241 H243 K271 V272 I290 N291 R300 G303 A305 T306 K308 R309 V312 K315 K319 Q322 R326 A331 F334 A335 K342 K343 T347 T349 P351 F355 L359	R30 H35 N42 K43 N44 K45 R46 Q47 Y49 V51 S52 A55 H57 Q58 T59 S60 T66 G67 R68 V70 R72 I73 P74 R75 G79 G80 T81 R83 Q86 N91 M92 R94 G95 R97 M98 F99 A100 P101 K103 R106 K107 V110 N113 H114 N115 E116 K117 R118 R137 G138 R140 K160 T161 S175 L178 K179 K185 L186 R187 A188 G189 K190 K192 Y193 R194 N195 R196 W198 R201 R202 Y208 K216 N220 T226 S231 N233 G240 H242 K270 V271 I289 N290 R299 G302 A304 T305 K307 R308 V311 K314 K318 Q321 R325 A330 F333 A334 K341 K342 T346 T348 P350 F354 L358
BS02	rna	D	A51 K193 Y194	A50 K192 Y193

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6qtz, PDBe:6qtz, PDBj:6qtz
PDBsum	6qtz
PubMed	31115337
UniProt	P10664\|RL4A_YEAST Large ribosomal subunit protein uL4A (Gene Name=RPL4A)

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