Structure of PDB 6qtp Chain D

Receptor sequence
>6qtpD (length=190) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEK
ARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHI
RTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEH
RALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYA
3D structure
PDB6qtp Mechanistic and Structural Basis for the Actions of the Antibacterial Gepotidacin against Staphylococcus aureus Gyrase.
ChainD
Resolution2.37 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D K460 L462 N463 K466 H515 V626 R629 K44 L46 N47 K50 H99 V176 R179
BS02 dna D E435 D437 S438 G459 D512 E19 D21 S22 G43 D96
BS03 MN D E435 D508 E19 D92
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:6qtp, PDBe:6qtp, PDBj:6qtp
PDBsum6qtp
PubMed30757898
UniProtP66937|GYRB_STAAN DNA gyrase subunit B (Gene Name=gyrB)

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