Structure of PDB 6qkc Chain D

Receptor sequence
>6qkcD (length=396) Species: 10116 (Rattus norvegicus) [Search protein sequence]
VVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIV
GDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPF
MSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSR
EFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTAN
LAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDK
MWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCD
TMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYD
KGECGGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR
3D structure
PDB6qkc Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP gamma 8.
ChainD
Resolution4.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 E2Q D Y450 P478 L479 T480 R485 E705 M708 Y55 P83 L84 T85 R90 E286 M289
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0038023 signaling receptor activity
Biological Process
GO:0006811 monoatomic ion transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qkc, PDBe:6qkc, PDBj:6qkc
PDBsum6qkc
PubMed30872532
UniProtP19491|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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