Structure of PDB 6qfa Chain D

Receptor sequence
>6qfaD (length=333) Species: 9606 (Homo sapiens) [Search protein sequence]
NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDY
TLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVH
GVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY
GYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPR
LSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITT
VLTMTTINTHLRETLPKIPYVTAIDMYLMGCFVFVFLALLEYAFVNYIFF
SQPARAAAIDRWSRIVFPFTFSLFNLVYWLYYV
3D structure
PDB6qfa Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
ChainD
Resolution2.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HSM D E155 F200 Y205 E148 F193 Y198
BS02 HSM D D43 Y62 D36 Y55
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0004890 GABA-A receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qfa, PDBe:6qfa, PDBj:6qfa
PDBsum6qfa
PubMed33408403
UniProtP28472|GBRB3_HUMAN Gamma-aminobutyric acid receptor subunit beta-3 (Gene Name=GABRB3)

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