Structure of PDB 6qdv Chain D

Receptor sequence
>6qdvD (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
TLVIPKNAAEEQKLKLERLMKNPDKAVPIPEKMSEWAPRPPPEFVRDVMG
SSAGAGSGEFHVYRHLRRREYQRQDYMDAMAEKQKLDAEFQKRLEKNKIA
AEEQTAKRRKKRQKLKEKKLLAK
3D structure
PDB6qdv A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation.
ChainD
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna D T20 L21 V22 I23 P24 R37 D66 G77 H80 H84 T124 R127 R128 R131 K133 K135 K137 T1 L2 V3 I4 P5 R18 D47 G58 H61 H65 T105 R108 R109 R112 K114 K116 K118
BS02 rna D G73 S76 G54 S57
Gene Ontology
Molecular Function
GO:0003725 double-stranded RNA binding

View graph for
Molecular Function
External links
PDB RCSB:6qdv, PDBe:6qdv, PDBj:6qdv
PDBsum6qdv
PubMed30705154
UniProtQ9H875|PKRI1_HUMAN PRKR-interacting protein 1 (Gene Name=PRKRIP1)

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