Structure of PDB 6q1r Chain D

Receptor sequence
>6q1rD (length=283) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
NAMVVTLDGEILQPGMPLLHADDLAAVRGDGVFETLLVRDGRACLVEAHL
QRLTQSARLMDLPEPDLPRWRRAVEVATQRWVASTADEGALRLIYSRGRE
GGSAPTAYVMVSPVPARVIGARRDGVSAITLDRGLPADGGDAMPWLIASA
KTLSYAVNMAVLRHAARQGAGDVIFVSTDGYVLEGPRSTVVIATPCLLTP
PPWYPILRGTTQQALFEVARAKGYDCDYRALRVADLFDSQGIWLVSSMTL
AARVHTLDGRRLPRTPIAEVFAELVDAAIVSDR
3D structure
PDB6q1r A hypothetical aminotransferase from Mycobacterium tuberculosis
ChainD
Resolution2.702 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.21: D-amino-acid transaminase.
4.1.3.38: aminodeoxychorismate lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP D R50 K149 Y153 R185 S186 T187 L213 G215 T216 S252 S253 R52 K151 Y155 R187 S188 T189 L207 G209 T210 S246 S247
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008483 transaminase activity
GO:0008696 4-amino-4-deoxychorismate lyase activity
GO:0016829 lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0019752 carboxylic acid metabolic process
GO:0046394 carboxylic acid biosynthetic process
GO:0046654 tetrahydrofolate biosynthetic process
GO:0046656 folic acid biosynthetic process
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane

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Cellular Component
External links
PDB RCSB:6q1r, PDBe:6q1r, PDBj:6q1r
PDBsum6q1r
PubMed
UniProtQ79FW0|BALDT_MYCTU Bifunctional aminodeoxychorismate lyase / D-amino acid transaminase (Gene Name=Rv0812)

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