Structure of PDB 6pwv Chain D

Receptor sequence
>6pwvD (length=357) Species: 9606 (Homo sapiens) [Search protein sequence]
KQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFS
AQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGD
LYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAW
YFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQS
IGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFE
EKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKS
CTVSINFGPCFKYPPKDLTYRPMSDMGWGAVVEHTLADVLYHVETEVDGR
RSPPWEP
3D structure
PDB6pwv Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
ChainD
Resolution6.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D Q209 K421 Q32 K244
Gene Ontology
Cellular Component
GO:0048188 Set1C/COMPASS complex

View graph for
Cellular Component
External links
PDB RCSB:6pwv, PDBe:6pwv, PDBj:6pwv
PDBsum6pwv
PubMed31804488
UniProtQ9UBL3|ASH2L_HUMAN Set1/Ash2 histone methyltransferase complex subunit ASH2 (Gene Name=ASH2L)

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