Structure of PDB 6om2 Chain D

Receptor sequence
>6om2D (length=330) Species: 9606 (Homo sapiens) [Search protein sequence]
NEINTQVTPGEANFMLKVHPLKKYPVDLYYLVDVSASMHNNIEKLNSVGN
DLSRKMAFFSRDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDCMPP
HGYIHVLSLTENITEFEKAVHRQKISGNIDTPEGGFDAMLQAAVCESHIG
WRKEAKRLLLVMTDQTSHLALDSKLAGIVCPNDGNCHLKNNVYVKSTTME
HPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGTIAGEIESKAA
NLNNLVVEAYQKLISEVKVQVENQVQGYFNITAICPDGSRKPGMEGCRNV
SNDEVLFNVTVTMYAIIKPIGFNETAKIHI
3D structure
PDB6om2 General structural features that regulate integrin affinity revealed by atypical alpha V beta 8.
ChainD
Resolution2.77 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D S114 A115 S116 H118 N207 I208 E212 S35 A36 S37 H39 N128 I129 E133
BS02 CA D D151 N207 D209 T210 P211 E212 D72 N128 D130 T131 P132 E133
BS03 MG D S114 S116 E212 S35 S37 E133
External links
PDB RCSB:6om2, PDBe:6om2, PDBj:6om2
PDBsum6om2
PubMed31792290
UniProtP26012|ITB8_HUMAN Integrin beta-8 (Gene Name=ITGB8)

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