Structure of PDB 6o7i Chain D

Receptor sequence

>6o7iD (length=272) Species: 523850 (Thermococcus onnurineus NA1) [Search protein sequence]

MDRRFYGKIVIKGKIKAVTGLHIGSPVIKDPHTGLPYIPGSSLKGRLRSL
FEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHV
CPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAI
TEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKN
LLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSI
DAREKSVSDIFDSLFSEVEGKL

3D structure

PDB

6o7i Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.

Chain

Resolution

3.2 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	D	G24 S53 S54 K56 G57 R58 R60 G129 A130 S131 N136 S139 I167 E168 V169 I171 R173 S176 P180 R181 Y224 G227 R231	G24 S41 S42 K44 G45 R46 R48 G117 A118 S119 N124 S127 I155 E156 V157 I159 R161 S164 P168 R169 Y212 G215 R219
BS02	rna	D	N106 K133 P180 R181	N94 K121 P168 R169
BS03	ZN	D	H111 C113 C122 C125	H99 C101 C110 C113

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0004519	endonuclease activity

	Biological Process
GO:0051607	defense response to virus

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Molecular Function

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Biological Process

External links

PDB	RCSB:6o7i, PDBe:6o7i, PDBj:6o7i
PDBsum	6o7i
PubMed	31326272
UniProt	B6YWC0

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