Structure of PDB 6o5x Chain D

Receptor sequence
>6o5xD (length=99) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDIDLPGRWKPKLIVGI
GGFVKVRQYEQVPIEIAGHKVVGTVLIGPTPSNIIGRNLMTQLGATLNF
3D structure
PDB6o5x Highly Drug-Resistant HIV-1 Protease Mutant PRS17 Shows Enhanced Binding to Substrate Analogues.
ChainD
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D25 T26 G27
Catalytic site (residue number reindexed from 1) D25 T26 G27
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0Q4 D K45 L46 K45 L46 MOAD: Ki=22nM
BS02 0Q4 D D25 G27 A28 D29 D30 L46 I47 V48 P81 S82 D25 G27 A28 D29 D30 L46 I47 V48 P81 S82 MOAD: Ki=22nM
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6o5x, PDBe:6o5x, PDBj:6o5x
PDBsum6o5x
PubMed31172041
UniProtI7BFC3

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