Structure of PDB 6nvy Chain D

Receptor sequence
>6nvyD (length=536) Species: 1221996 (Bacillus thermotolerans) [Search protein sequence]
SNAMIVGEDKSKTGNALLFSGPQVGFVAPGFLYEVGLHAPGFDMEGSGFI
GYPFIMFGANKHIALTATAGYGNVTDIFEEKLHPNDPTQYFYKGEWREME
KRTETFTVRGEDGKPEQVETVFYRTVHGPVISIDEERGVAYSKSWSFRGT
EAQSMQAYMKANWAKNLKEFEEAASEYTMSLNWYYADKRGNIAYYHAGKQ
PVRNEEIDERLPTPGTGEYDWQGFQPFEQNPQAVNPDNGYVVNWNNKPSQ
EWRNGERSFYWGKDNRVQQFINGMEEREKVDLEDLNEINYTASFAQLRTH
YFKPLLIEVLKENQSDNESYPYLIKQLEQWNNLKEDKNKDGLYDAGVAAF
FDKWWSITHDELFAQPLGSVSNLTQEITDHRYGATLAYKILAGEETNYPW
MSKEEAEQIIINSADQALAELHEEKGTKAENWRMPIDTMTFGETSLIGVQ
HGYGSDTPIIEMNRGSENHYLEMTPSGPKGFNITPPGQVGFIHKDGTVSE
HYEDQVQMFANWEFKPFLFDRKEVREAAVSITDLNV
3D structure
PDB6nvy Crystal structures and protein engineering of three different penicillin G acylases from Gram-positive bacteria with different thermostability.
ChainD
Resolution2.27 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S1 Q23 A69 N245 N468
Catalytic site (residue number reindexed from 1) S1 Q23 A69 N245 N468
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA D N73 T75 D76 E256 N73 T75 D76 E256
BS02 CA D D336 N338 D340 L342 D344 D336 N338 D340 L342 D344
BS03 CA D D284 E287 D284 E287
BS04 CA D E8 G14 E8 G14
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
Biological Process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6nvy, PDBe:6nvy, PDBj:6nvy
PDBsum6nvy
PubMed31227867
UniProtA0A0F5I5V4

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