Structure of PDB 6n9a Chain D

Receptor sequence
>6n9aD (length=330) Species: 2336 (Thermotoga maritima) [Search protein sequence]
EGRMRVLGIETSCDETAVAVLDDGKNVVVNFTVSQIEVHQKFGGVVPEVA
ARHHLKNLPILLKKAFEKVPPETVDVVAATYGPGLIGALLVGLSAAKGLA
ISLEKPFVGVNHVEAHVQAVFLANPDLKPPLVVLMVSGGHTQLMKVDEDY
SMEVLGETLDDSAGEAFDKVARLLGLGYPGGPVIDRVAKKGDPEKYSFPR
PMLDDDSYNFSFAGLKTSVLYFLQREKGYKVEDVAASFQKAVVDILVEKT
FRLARNLGIRKIAFVGGVAANSMLREEVRKRAERWNYEVFFPPLELCTDN
ALMVAKAGYEKAKRGMFSPLSLNADPNLNV
3D structure
PDB6n9a Conformational communication mediates the reset step in t6A biosynthesis.
ChainD
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.234: N(6)-L-threonylcarbamoyladenine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KG4 D S134 G135 G161 F164 D165 G178 P179 G264 V265 N268 S137 G138 G164 F167 D168 G181 P182 G267 V268 N271
BS02 ZN D H109 H113 H137 D296 H112 H116 H140 D299
BS03 ADP D R252 W282 Y284 R255 W285 Y287
BS04 ATP D K166 G211 K213 T214 K169 G214 K216 T217
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0046872 metal ion binding
GO:0061711 N(6)-L-threonylcarbamoyladenine synthase activity
Biological Process
GO:0002949 tRNA threonylcarbamoyladenosine modification
GO:0008033 tRNA processing
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6n9a, PDBe:6n9a, PDBj:6n9a
PDBsum6n9a
PubMed31114923
UniProtQ9WXZ2|TSAD_THEMA tRNA N6-adenosine threonylcarbamoyltransferase (Gene Name=tsaD)

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