Structure of PDB 6lp1 Chain D

Receptor sequence
>6lp1D (length=466) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
GLDKVMSLSSAVQDIKNGATLAVGGFGTGGMPHAIMQEIKKMGVRDLIIY
SDGAGVDGYGIGVLFENKQINKMIVSYVGNNKIFARQYLEGDVELEFCPQ
GSLAERMRAGGAGIPAFYTPTAVGTVLQTGGQITKYDKNGGVLKESTPRE
TRFFGGRLYCLENAIKTDFSIVKAWKGDRCGNLVFRGTARNFNVPVGQCG
QTVIAEVENLVENGDIDPDEVHLPGVYVDRVVVPERYQTLIEHRTVTGEE
VRQRIARRAALEFANGMYVNLGIGIPTESSNYIPAGVNVVLQSENGLIGM
GPFPTEDKVDADWINAGKQTISHLAGSALFDSATSFAMIRGGHMDLTMLG
ALEVAANGDLANFMIPGKLVKGPGGAMDLVSCGTRVVVTTTHCNKNGDPK
IVERCRLPVTGKHCVCRIITEYAVFDVVDGRLVLKEIAEDTTVDQVKKLT
GVGFDADNVITMPLAP
3D structure
PDB6lp1 The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei.
ChainD
Resolution2.01 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.3.5: 3-oxoacid CoA-transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA D Q211 D239 Q201 D229
Gene Ontology
Molecular Function
GO:0008260 succinyl-CoA:3-oxo-acid CoA-transferase activity
GO:0008410 CoA-transferase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0046950 cellular ketone body metabolic process
GO:0046952 ketone body catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6lp1, PDBe:6lp1, PDBj:6lp1
PDBsum6lp1
PubMed32763239
UniProtQ386P1

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