Structure of PDB 6lis Chain D

Receptor sequence
>6lisD (length=145) Species: 10497 (African swine fever virus) [Search protein sequence]
ATNFFIQPITEEAEAYYPPSVITNKRKDLGVDVYCCSDLVLQPGLNIVRL
HIKVACEHMGKKCGFKIMARSSMCTHERLLILANGIGLIDPGYVGELMLK
IINLGDTPVQIWAKECLVQLVAQGDHVPDHINILKRNQIFPLFAP
3D structure
PDB6lis Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development.
ChainD
Resolution1.998 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UMP D I90 Y94 M99 I89 Y93 M98
BS02 UMP D R71 S72 R70 S71
Gene Ontology
Molecular Function
GO:0004170 dUTP diphosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0009117 nucleotide metabolic process
Cellular Component
GO:0030430 host cell cytoplasm
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6lis, PDBe:6lis, PDBj:6lis
PDBsum6lis
PubMed33139328
UniProtQ65199|DUTP_ASFB7 Deoxyuridine 5'-triphosphate nucleotidohydrolase (Gene Name=Ba71V-131)

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