Structure of PDB 6jmt Chain D

Receptor sequence
>6jmtD (length=350) Species: 10090 (Mus musculus) [Search protein sequence]
RSSDVCADCNGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTA
WPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAE
FIRAKYQMLAFVHRLPCREDDSVTAKDLSKQLHSSVRTGNLETCLRLLSL
GAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVD
YARQGGHHELAERLIEIQYELTDRLAFYLCGRKPDHKSGQHFLIPQRADA
ALDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHS
TLVTVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQG
3D structure
PDB6jmt GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling.
ChainD
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D A266 K267 L277 L281 S324 T326 R327 G330 L334 F337 E341 D348 A261 K262 L272 L276 S315 T317 R318 G321 L325 F328 E332 D339
BS02 ZN D C11 C14 C31 C34 C6 C9 C26 C29
Gene Ontology
Molecular Function
GO:0005096 GTPase activator activity
Biological Process
GO:0007420 brain development
GO:0032012 regulation of ARF protein signal transduction

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Molecular Function

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Biological Process
External links
PDB RCSB:6jmt, PDBe:6jmt, PDBj:6jmt
PDBsum6jmt
PubMed32780989
UniProtQ9JLQ2|GIT2_MOUSE ARF GTPase-activating protein GIT2 (Gene Name=Git2)

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