Structure of PDB 6j9h Chain D

Receptor sequence
>6j9hD (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]
MDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPV
PERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIK
CLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGAL
GMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLGQSVSHDPH
SVEQIEWKHSVLDVERLGRDDFRKELERHARDMRL
3D structure
PDB6j9h Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis.
ChainD
Resolution2.31 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.17.17: tubulinyl-Tyr carboxypeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D M69 W74 I84 H85 I95 R96 L101 I104 P105 L132 Q133 Y134 H136 T137 F141 E163 A164 L165 P166 M1 W6 I16 H17 I27 R28 L33 I36 P37 L64 Q65 Y66 H68 T69 F73 E95 A96 L97 P98
Gene Ontology
Biological Process
GO:0045765 regulation of angiogenesis
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:6j9h, PDBe:6j9h, PDBj:6j9h
PDBsum6j9h
PubMed31171830
UniProtQ7L8A9|VASH1_HUMAN Tubulinyl-Tyr carboxypeptidase 1 (Gene Name=VASH1)

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