Structure of PDB 6j27 Chain D

Receptor sequence
>6j27D (length=344) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence]
VNKEALVQVAEEVRRATGLPVGWRDVERTLGALRATRDLWEAVRLSRVPL
RFLVPIWEGLARRGLLRVEEGLDLLAEVPAPRPGEAACPACEGRGLVGER
LPGRAAERFLAWAKERPEAIQDFDQGYVTPESTLARVALAWNWGDLEGKE
VLVLGDDDLTGLAAALTGLPKRVVVLDADPRIVRFLERAAKAEGLPLEAH
VHDLREPLPEAWVHAFHTFFTDPVEGPLGLQAFVGRGLLALEGEGCAGYV
GLTHVEASLAKWADFQRFLLENGAVITELRDGFHVYENWGYIEQMRAWPW
LPVKRRPEKPWYTSALIRLELLRRADLENARVEGDLQDEEATTY
3D structure
PDB6j27 The C-terminal flexible region of branched-chain polyamine synthase facilitates substrate specificity and catalysis.
ChainD
Resolution1.66 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.5.1.128: N(4)-bis(aminopropyl)spermidine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE D C97 C100 C88 C91
BS02 MTA D F132 Q134 G164 D166 D186 A187 D212 L213 F242 F123 Q125 G155 D157 D177 A178 D203 L204 F233
BS03 N4P D D133 G135 D166 D167 D231 P232 E234 G260 W298 Y300 Y321 T352 D124 G126 D157 D158 D222 P223 E225 G251 W289 Y291 Y312 T343
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0046872 metal ion binding
Biological Process
GO:0006596 polyamine biosynthetic process
GO:0009058 biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6j27, PDBe:6j27, PDBj:6j27
PDBsum6j27
PubMed31162806
UniProtQ72L89

[Back to BioLiP]