Structure of PDB 6iyw Chain D

Receptor sequence
>6iywD (length=264) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
TFQTSSPAHLTMPYVMPGDGEVVGVGEPVAIRFDENIADRGAAEKAIKIT
TNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDLGEGMFGED
NVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGI
YIVGSRYKHIIMDSSTYGVPVNSPNGYRTDVDWATQISYSGVFVHSAPWS
VGAQGHTNTSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGGTLPGIDGL
GDWNIPWDQWRAGN
3D structure
PDB6iyw The 1-beta-methyl group confers a lower affinity of l,d-transpeptidase LdtMt2 for ertapenem than for imipenem.
ChainD
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IM2 D M303 Y308 Y318 S331 G332 H352 C354 M162 Y167 Y177 S190 G191 H211 C213
Gene Ontology
Molecular Function
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:6iyw, PDBe:6iyw, PDBj:6iyw
PDBsum6iyw
PubMed30686533
UniProtI6Y9J2|LDT2_MYCTU L,D-transpeptidase 2 (Gene Name=ldtB)

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