Structure of PDB 6iqw Chain D

Receptor sequence
>6iqwD (length=271) Species: 523850 (Thermococcus onnurineus NA1) [Search protein sequence]
MDRRFYGKIVIKGKIKAVTGLHIGSQPVIKDPHTGLPYIPGSSLKGRLRS
LFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIH
VCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEA
ITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIK
NLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVS
IDAREKSVSDILSGFDSLFSE
3D structure
PDB6iqw Cryo-EM structure of Type III-A CRISPR effector complex.
ChainD
Resolution3.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna D I23 G24 S53 S54 K56 G57 R58 R60 S61 G129 A130 S131 N136 I167 E168 V169 I171 Y224 G226 G227 S228 S230 R231 I23 G24 S42 S43 K45 G46 R47 R49 S50 G118 A119 S120 N125 I156 E157 V158 I160 Y213 G215 G216 S217 S219 R220
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6iqw, PDBe:6iqw, PDBj:6iqw
PDBsum6iqw
PubMed30459428
UniProtB6YWC0

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