Structure of PDB 6ih1 Chain D

Receptor sequence
>6ih1D (length=237) Species: 345073 (Vibrio cholerae O395) [Search protein sequence]
SLDFDFTMAFQPIVNCRTKEIFGYEALVRGLNNESAYSVISRVNEDNRYL
FDQMCRVKAIALAAKLGLTSKLSINFLPNAIYVPERCIRTTLEAAKRYQF
PIENIMFEFTEAERVEDVNHIKRIVEYYKSLGFQTAIDDFGSGYSGLNLL
ADFQTNIVKVDMGLIRNIHADQVRQSIMKNCLKLFSDLNIQPLAEGVESH
AEFAWLKAAGVELMQGYYFAKPGFESLPSVNPEFSEA
3D structure
PDB6ih1 Structures of c-di-GMP/cGAMP degrading phosphodiesterase VcEAL: identification of a novel conformational switch and its implication.
ChainD
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.52: cyclic-guanylate-specific phosphodiesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C2E D Q31 L47 V48 R49 A56 I60 C75 N95 L97 M182 E215 G216 E218 G236 Y237 Q11 L27 V28 R29 A36 I40 C55 N75 L77 M162 E195 G196 E198 G216 Y217
BS02 CA D E45 N95 E128 D158 E25 N75 E108 D138
BS03 CA D D158 D159 E215 D138 D139 E195
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6ih1, PDBe:6ih1, PDBj:6ih1
PDBsum6ih1
PubMed31647518
UniProtA0A0H3AJ04

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