Structure of PDB 6i5n Chain D

Receptor sequence
>6i5nD (length=151) Species: 9606 (Homo sapiens) [Search protein sequence]
SMQAARLAKALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSD
YLLTISVKTSAGPTNLRIEYQDGKFRLDSILAAFDSVVHLIDYYVQMCKT
VHLYLTKPLYTSAPSLQHLCRLTINKCTGAIWGLPLPTRLKDYLEEYKFQ
V
3D structure
PDB6i5n Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase.
ChainD
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D V55 R73 S75 S76 T83 A90 G91 P92 T93 N94 L95 R96 D107 S108 V26 R44 S46 S47 T54 A61 G62 P63 T64 N65 L66 R67 D78 S79
BS02 peptide D Y128 M132 X133 V148 H149 L150 Y93 M97 X98 V101 H102 L103
Gene Ontology
Biological Process
GO:0035556 intracellular signal transduction

View graph for
Biological Process
External links
PDB RCSB:6i5n, PDBe:6i5n, PDBj:6i5n
PDBsum6i5n
PubMed31182716
UniProtO14508|SOCS2_HUMAN Suppressor of cytokine signaling 2 (Gene Name=SOCS2)

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