Structure of PDB 6i5j Chain D

Receptor sequence
>6i5jD (length=169) Species: 9606 (Homo sapiens) [Search protein sequence]
SMQAARLAKALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSD
YLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYY
VQMCKDKRTGPEAPRNGTVHLYLTKPLYTSAPSLQHLCRLTINKCTGAIW
GLPLPTRLKDYLEEYKFQV
3D structure
PDB6i5j Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase.
ChainD
Resolution2.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D V55 R73 S75 S76 A90 T93 N94 L95 R96 D107 S108 L116 V26 R44 S46 S47 A61 T64 N65 L66 R67 D78 S79 L87
BS02 peptide D M132 X133 R137 T147 V148 H149 M103 X104 R108 T118 V119 H120
Gene Ontology
Biological Process
GO:0035556 intracellular signal transduction

View graph for
Biological Process
External links
PDB RCSB:6i5j, PDBe:6i5j, PDBj:6i5j
PDBsum6i5j
PubMed31182716
UniProtO14508|SOCS2_HUMAN Suppressor of cytokine signaling 2 (Gene Name=SOCS2)

[Back to BioLiP]