Structure of PDB 6i2n Chain D

Receptor sequence
>6i2nD (length=336) [Search protein sequence]
DPTGVEPGDHLKERSMLSYGNVLDLNHLDIDEPTGQTADWLSIIVYLTSF
VVPILLKALYMLTTRGRQTTKDNKGTRIRFKDDSSFEDVNGIRKPKHLYV
SLPNAQSSMKAEEITPGRYRTAVCGLYPAQIKARQMISPVMSVIGFLALA
KDWSDRIEQWLIEPCKATNRDYLRQRQVALGNMETKESKAIRQHAEAAGC
SMIEDIESPSSIWVFAGAPDRCPPTCLFIAGIAELGAFFSILQDMRNTIM
ASKTVGTSEEKLRKKSSFYQSYLRRTQSMGIQLGQRIIVLFMVAWGKEAV
DNFHLGDDMDPELRTLAQSLIDVKVKEISNQEPLKL
3D structure
PDB6i2n High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms.
ChainD
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna D P182 R197 S359 F361 S364 R368 P103 R118 S266 F268 S271 R275
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0033668 symbiont-mediated suppression of host apoptosis
GO:0052150 symbiont-mediated perturbation of host apoptosis
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:0044177 host cell Golgi apparatus
GO:0044220 host cell perinuclear region of cytoplasm
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6i2n, PDBe:6i2n, PDBj:6i2n
PDBsum6i2n
PubMed30638449
UniProtP05133|NCAP_HANTV Nucleoprotein (Gene Name=N)

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