Structure of PDB 6hxi Chain D

Receptor sequence
>6hxiD (length=616) Species: 2223 (Methanothrix soehngenii) [Search protein sequence]
KDYVLFDINTKAFVYGYQTNAIQRMLDFDYVCKRSSPSISAIINPSRAGI
HKAFWGTKEIILPMYKTIPLAALAYPEADVMVNFASHRSAFETTMEALKE
DTIRIVAVIAEGVPERQSRVMAATARKLDKIVIGPATVGGMTAGAFRIGN
TAGTIENIIASKLYRPGCVGFVSKSGGMLNEAFNIISRNSDGIYEGVAIG
GDRYPGSNMLDHILRYERNPAIKMIACLGELGGEDEYMIIQALKEKKITK
PLVAWVTGTCSPYLPASVQFGHAGAKANTEKETAQAKNDAFRQAGAYVPR
SFDDYGEMVRQVYDMLLTRGIVQKFDEPEVPRIPTDYSKALATGDIRKPT
TFICTISDDSGEELLYAGKKLSDVLDRKMGIGGVIGLLWFKKELPEYAAH
FIELVIQIVADHGPAVSGAHNAIVASCAGKDLISSLCSGLLTIGPRFGGA
IDDAAREFKRAQETGLAPEQFVGEMKKKGINIPGIGHKIKSVKNPDKRVQ
LLISYARANFPSTELLNYALQVEELTTAKKGNLILNVDGCIGILFIDLMS
SCGAFSKEEIDEVVRLGYLNGLFALGRSIGLIGHILDQKRLGSRLYRHPA
EDIAYMMPSEEEIQCK
3D structure
PDB6hxi Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
ChainD
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.2.1.5: succinate--CoA ligase (ADP-forming).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA D F87 S89 R91 S92 I112 A139 T140 V141 F84 S86 R88 S89 I109 A136 T137 V138
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003878 ATP citrate synthase activity
GO:0004775 succinate-CoA ligase (ADP-forming) activity
GO:0016740 transferase activity
GO:0016874 ligase activity
GO:0043758 acetate-CoA ligase (ADP-forming) activity
GO:0046912 acyltransferase activity, acyl groups converted into alkyl on transfer
Biological Process
GO:0006085 acetyl-CoA biosynthetic process
GO:0006629 lipid metabolic process
GO:0006633 fatty acid biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6hxi, PDBe:6hxi, PDBj:6hxi
PDBsum6hxi
PubMed30944476
UniProtA0A1V4VDZ9

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