Structure of PDB 6h9e Chain D

Receptor sequence
>6h9eD (length=483) Species: 1494 (Clostridium cochlearium) [Search protein sequence]
MELKNKKWTDEEFHKQREEVLQQWPTGKEVDLQEAVDYLKKIPAEKNFAE
KLVLAKKKGITMAQPRAGVALLDEHIELLRYLQDEGGADFLPSTIDAYTR
QNRYDECENGIKESEKAGRSLLNGFPGVNHGVKGCRKVLEAVNLPLQARH
GTPDSRLLAEIIHAGGWTSNEGGGISYNVPYAKNVTIEKSLLDWQYCDRL
VGFYEEQGVHINREPFGPLTGTLVPPSMSNAVGITEALLAAEQGVKNITV
GYGECGNMIQDIAALRCLEEQTNEYLKAYGYNDVFVTTVFHQWMGGFPQD
ESKAFGVIVTATTIAALAGATKVIVKTPHEAIGIPTKEANAAGIKATKMA
LNMLEGQRMPMSKELETEMAVIKAETKCILDKMFELGKGDLAIGTVKAFE
TGVMDIPFGPSKYNAGKMMPVRDNLGCVRYLEFGNVPFTEEIKNYNRERL
QERAKFEGRDVSFQMVIDDIFAVGKGRLIGRPE
3D structure
PDB6h9e Structure-Based Demystification of Radical Catalysis by a Coenzyme B 12 Dependent Enzyme-Crystallographic Study of Glutamate Mutase with Cofactor Homologues.
ChainD
Resolution1.82 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R100 E171
Catalytic site (residue number reindexed from 1) R100 E171
Enzyme Commision number 5.4.99.1: methylaspartate mutase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 B12 D A97 R100 N123 Y181 T220 M294 G295 G296 F297 E330 A331 G333 I334 F471 A97 R100 N123 Y181 T220 M294 G295 G296 F297 E330 A331 G333 I334 F471
BS02 FWK D R66 A67 G68 T94 N123 K326 E330 I334 P335 R66 A67 G68 T94 N123 K326 E330 I334 P335
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0016853 isomerase activity
GO:0016866 intramolecular transferase activity
GO:0031419 cobalamin binding
GO:0050097 methylaspartate mutase activity
Biological Process
GO:0019553 glutamate catabolic process via L-citramalate
GO:0019670 anaerobic glutamate catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6h9e, PDBe:6h9e, PDBj:6h9e
PDBsum6h9e
PubMed35793207
UniProtP80077|GLME_CLOCO Glutamate mutase epsilon subunit (Gene Name=glmE)

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