Structure of PDB 6h3m Chain D

Receptor sequence
>6h3mD (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB6h3m Substitution of an Internal Disulfide Bridge with a Diselenide Enhances both Foldability and Stability of Human Insulin.
ChainD
Resolution1.821 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D V2 Q4 V2 Q4
BS02 peptide D S9 H10 V12 E13 Y16 F24 F25 Y26 S9 H10 V12 E13 Y16 F24 F25 Y26
BS03 peptide D F1 H5 L6 C7 L15 V18 C19 R22 G23 F24 F25 P28 K29 F1 H5 L6 C7 L15 V18 C19 R22 G23 F24 F25 P28 K29
BS04 peptide D N3 L17 V18 N3 L17 V18
BS05 peptide D Y16 G20 E21 Y16 G20 E21
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:6h3m, PDBe:6h3m, PDBj:6h3m
PDBsum6h3m
PubMed31012517
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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