Structure of PDB 6gw3 Chain D

Receptor sequence
>6gw3D (length=380) Species: 3483 (Cannabis sativa) [Search protein sequence]
LRAEGPASVLAIGTANPENILLQDEFPDYYFRVTKSEHMTQLKEKFRKIC
DKSMIRKRNCFLNEEHLKQNPRLVEHEMQTLDARQDMLVVEVPKLGKDAC
AKAIKEWGQPKSKITHLIFTSASTTDMPGADYHCAKLLGLSPSVKRVMMY
QLGCYGGGTVLRIAKDIAENNKGARVLAVCCDIMACLFRGPSESDLELLV
GQAIFGDGAAAVIVGAEPDESVGERPIFELVSTGQTILPNSEGTIGGHIR
EAGLIFDLHKDVPMLISNNIEKCLIEAFTPIGISDWNSIFWITHPGGKAI
LDKVEEKLHLKSDKFVDSRHVLSEHGNMSSSTVLFVMDELRKRSLEEGKS
TTGDGFEWGVLFGFGPGLTVERVVVRSVPI
3D structure
PDB6gw3 Structure of a PKS class III from Cannabis sativa
ChainD
Resolution1.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.206: 3,5,7-trioxododecanoyl-CoA synthase.
4.4.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 COA D K51 K55 A157 L199 E200 V203 L261 K263 G299 G300 K301 A302 K48 K52 A154 L196 E197 V200 L258 K260 G296 G297 K298 A299
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0016829 lyase activity
Biological Process
GO:0009058 biosynthetic process
GO:0016114 terpenoid biosynthetic process
GO:0030639 polyketide biosynthetic process
GO:1901696 cannabinoid biosynthetic process

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Molecular Function

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Biological Process
External links
PDB RCSB:6gw3, PDBe:6gw3, PDBj:6gw3
PDBsum6gw3
PubMed
UniProtB1Q2B6|OLIS_CANSA 3,5,7-trioxododecanoyl-CoA synthase (Gene Name=OLS)

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