Structure of PDB 6gnw Chain D

Receptor sequence
>6gnwD (length=115) Species: 8175 (Sparus aurata) [Search protein sequence]
CPLMVKILDAVKGTPAGSVALKVSQKTADGGWTQIATGVTDATGEIHNLI
TEQQFPAGVYRVEFDTKAYWTNQGSTPFHEVAEVVFDAHPEGHRHYTLAL
LLSPFSYTTTAVVSS
3D structure
PDB6gnw Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.
ChainD
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 F52 D L17 A108 L109 L110 T117 L8 A99 L100 L101 T108 MOAD: Kd=10.2uM
PDBbind-CN: -logKd/Ki=4.99,Kd=10.20uM
Gene Ontology
Molecular Function
GO:0005179 hormone activity
GO:0070324 thyroid hormone binding
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0007165 signal transduction
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6gnw, PDBe:6gnw, PDBj:6gnw
PDBsum6gnw
PubMed30226982
UniProtQ9PTT3

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