Structure of PDB 6gnq Chain D

Receptor sequence
>6gnqD (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB6gnq Monoclinic crystalline form of human insulin, complexed with meta-cresol
ChainD
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D C7 L11 L15 V18 C19 R22 G23 F24 F25 Y26 P28 C7 L11 L15 V18 C19 R22 G23 F24 F25 Y26 P28
BS02 peptide D L6 S9 H10 L6 S9 H10
BS03 peptide D H5 G8 S9 V12 E13 Y16 E21 G23 F24 F25 Y26 P28 H5 G8 S9 V12 E13 Y16 E21 G23 F24 F25 Y26 P28
BS04 peptide D F1 Q4 F1 Q4
BS05 CRS D H10 L11 H10 L11
BS06 IS8 D L6 H10 L6 H10
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:6gnq, PDBe:6gnq, PDBj:6gnq
PDBsum6gnq
PubMed
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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