Structure of PDB 6gnm Chain D

Receptor sequence
>6gnmD (length=115) Species: 8175 (Sparus aurata) [Search protein sequence]
CPLMVKILDAVKGTPAGSVALKVSQKTADGGWTQIATGVTDATGEIHNLI
TEQQFPAGVYRVEFDTKAYWTNQGSTPFHEVAEVVFDAHPEGHRHYTLAL
LLSPFSYTTTAVVSS
3D structure
PDB6gnm Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.
ChainD
Resolution2.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 27M D K15 L17 A108 K6 L8 A99 PDBbind-CN: -logKd/Ki=4.26,Kd=54.61uM
Gene Ontology
Molecular Function
GO:0005179 hormone activity
GO:0070324 thyroid hormone binding
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0007165 signal transduction
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6gnm, PDBe:6gnm, PDBj:6gnm
PDBsum6gnm
PubMed30226982
UniProtQ9PTT3

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