Structure of PDB 6f91 Chain D

Receptor sequence

>6f91D (length=742) Species: 818 (Bacteroides thetaiotaomicron)

EKLTDYVNPFVGTDGYGNVYPGAQIPFGGIQISPDTDSRFYDAASGYKYN
HLTLMGFSLTHLSGTGIPDLGDFLFIPGTGEMKLEPGTHEDPDQGYRSRY
SHDKEWASPNYYAVELADYGVKAEMTSGVRSGMFRFTYPESDNAFIMIDM
NHTLWQSCEWSNLRMINDSTITGYKLVKGWGPERHVYFTATFSKKLTGLR
FVQDKKPVIYNTSRFRSSYEAWGKNLMACISFDTKAGEEVTVKTAISAVS
TDGARNNMKELDGLTFNELRAKGEALWEKELGKYTLTADRKTKETFYTSA
YHAALHPFIFQDSDGQFRGLDKNIEKAEGFTNYTVFSLWDTYRALHPWFN
LVQQEVNADIANSMLAHYDKSVEKMLPIWSFYGNETWCMIGYHAVSVLAD
MIVKEVKGFDYERAYEAMKTTAMNSNYDCLPEYREMGYVPFDKEAESVSK
TLEYAYDDYCIAQAAKKLGKEDDYHYFLNRALSYQTLIDPETKYMRGRDS
KGDWRTPFTPVAYGWGDITEGFTMQYTWYVPQDVQGYINEAGKELFRKRL
DELFTVELGRIGAYWHGNEPCHHVAYLYNYLKEPWKCQKWIRTIVDRFYG
NTPDALSGNDDCGQMSAWYMFNCIGFYPVAPSSNIYNIGSPCAEAITVRM
SNGKNIEMTADNWSPKNLYVKELYVNGKKYDKSYLTYDDIRDGVKLRFVM
SGKPNYKRAVSDEAVPPSISLPEKTMKYKSSIGFLEHHHHHH

3D structure

• PDB: 6f91 Bacteroides thetaiotaomicron generates diverse alpha-mannosidase activities through subtle evolution of a distal substrate-binding motif.
• Chain: D
• Resolution: 1.8 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CA	D	G589 E591 D633	G567 E569 D611

Gene Ontology

Molecular Function

• GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity
• GO:0030246 carbohydrate binding
• GO:0046872 metal ion binding

Biological Process

• GO:0005975 carbohydrate metabolic process
• GO:0006516 glycoprotein catabolic process

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:6f91, PDBe:6f91, PDBj:6f91
• PDBsum: 6f91
• PubMed: 29717710
• UniProt: Q8A0Q6