Structure of PDB 6f6w Chain D

Receptor sequence
>6f6wD (length=1242) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
VNFFDELRIGLATADDIRNWSYGEVKKPETINYRTLKPEKDGLFCEKIFG
PTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTH
IWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITSVDDEMRHNELSTLEA
EMAVEKKAVEDQRDADLEARAQKLEADLAELEDVRRKVRDSGEREMRQLR
DRAQRELDRLDEIWNTFTKLAPKQLIVDEVLYRELQDRYGEYFTGAMGAE
SIKKLIENFDIDAEAESLREVIRSGKGQKKLRALKRLKVVAAFQQSGNSP
MGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLID
LGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGK
QGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKR
LVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGI
QAFEPQLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILM
LSSNNILSPASGKPLAMPRLDMVTGLYYLTTLVEGATGEYQAATKDAPEQ
GVYSSPAEAIMAMDRGALSVRAKIKVRLTELRPPTDLEAQLFENGWKPGD
AWTAETTLGRVMFNELLPKSYPFVNEQMHKKVQARIINDLAERFPMIVVA
QTVDKLKDAGFYWATRSGVTVSMADVLVPPQKQEILERHEAEADAIERKY
QRGALNHTERNESLVKIWQDATEEVGKALEEFYPADNPIITIVKSGATGN
LTQTRTLAGMKGLVTNPKGEFIPRPIKSSFREGLTVLEYFINTHGARKGL
ADTALRTADSGYLTRRLVDVSQDVIVREHDCETERGINVTLAERGPDIRD
AHVETSAFARTLATDAVDANGNVIIERGHDLGDPAIDALLAAGITTVKVR
SVLTCTSATGVCAMCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTGG
LPRVQELFEARVPRNKAPIADVAGRVRLEESDKFFKITIVPDDGGEEVVY
DKLSKRQRLRVIGVLSDGDHVEVGDQLMEGAADPHEVLRVQGPREVQIHL
VKEVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTEFLPGSLTERA
EFEAENRRVVAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINC
RSDKLNGLKENVIIGKLIPAGTGISRYRNIQVQPTEEARAAA
3D structure
PDB6f6w The Core and Holoenzyme Forms of RNA Polymerase fromMycobacterium smegmatis.
ChainD
Resolution3.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D C890 C974 C881 C962
BS02 ZN D C60 C75 C57 C72
BS03 MG D D535 D537 D526 D528
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6f6w, PDBe:6f6w, PDBj:6f6w
PDBsum6f6w
PubMed30478083
UniProtA0QS66|RPOC_MYCS2 DNA-directed RNA polymerase subunit beta' (Gene Name=rpoC)

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